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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH8A1
All Species:
17.88
Human Site:
S23
Identified Species:
35.76
UniProt:
Q9H2A2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2A2
NP_072090.1
487
53401
S23
G
K
F
L
P
C
S
S
Y
I
D
S
Y
D
P
Chimpanzee
Pan troglodytes
XP_001170111
490
53679
S23
G
K
F
L
P
C
S
S
Y
I
D
S
Y
D
P
Rhesus Macaque
Macaca mulatta
XP_001101362
515
55911
G53
S
E
V
P
A
P
D
G
H
S
G
S
H
L
S
Dog
Lupus familis
XP_533415
487
53149
S23
G
K
F
V
P
C
N
S
Y
I
D
S
Y
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH00
487
53645
S23
G
K
F
L
P
C
N
S
Y
I
D
S
Y
D
P
Rat
Rattus norvegicus
P13601
501
54541
K36
W
H
N
S
L
N
G
K
K
F
P
V
I
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509667
487
53578
S23
G
K
F
V
P
T
S
S
H
L
D
S
F
D
P
Chicken
Gallus gallus
P27463
509
55791
I33
I
K
Y
T
K
I
F
I
N
N
E
W
H
D
S
Frog
Xenopus laevis
Q6GNL7
902
99964
Q304
G
K
M
I
P
A
S
Q
Y
F
K
T
A
D
S
Zebra Danio
Brachydanio rerio
Q66I21
487
53336
K23
G
K
F
V
P
C
S
K
L
I
D
S
F
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509203
506
55370
K41
N
E
F
A
R
S
E
K
L
M
D
S
V
N
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YU0
501
54342
K35
F
I
D
A
A
S
G
K
T
F
E
T
I
D
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
86
87.2
N.A.
89.9
38.3
N.A.
80.6
38.3
23.7
74.1
N.A.
N.A.
N.A.
49.4
N.A.
Protein Similarity:
100
94.2
89.1
95
N.A.
95.4
56.8
N.A.
90.3
55.5
36.5
87.6
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
6.6
N.A.
66.6
13.3
40
73.3
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
13.3
N.A.
93.3
33.3
53.3
86.6
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
17
9
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
9
0
0
0
59
0
0
75
0
% D
% Glu:
0
17
0
0
0
0
9
0
0
0
17
0
0
0
0
% E
% Phe:
9
0
59
0
0
0
9
0
0
25
0
0
17
0
0
% F
% Gly:
59
0
0
0
0
0
17
9
0
0
9
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
17
0
0
0
17
0
0
% H
% Ile:
9
9
0
9
0
9
0
9
0
42
0
0
17
0
0
% I
% Lys:
0
67
0
0
9
0
0
34
9
0
9
0
0
0
0
% K
% Leu:
0
0
0
25
9
0
0
0
17
9
0
0
0
9
0
% L
% Met:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
9
17
0
9
9
0
0
0
17
0
% N
% Pro:
0
0
0
9
59
9
0
0
0
0
9
0
0
0
75
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
9
0
17
42
42
0
9
0
67
0
0
25
% S
% Thr:
0
0
0
9
0
9
0
0
9
0
0
17
0
0
0
% T
% Val:
0
0
9
25
0
0
0
0
0
0
0
9
9
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
42
0
0
0
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _